loading...| Preferred Name |
Moexipril |
|
| Synonyms |
MOEXIPRIL Moexipril |
|
| Definitions |
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, moexipril is hydrolyzed into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83967 |
|
| CAS_Registry |
103775-10-6 |
|
| Chemical_Formula |
C27H34N2O7 |
|
| code |
C83967 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, moexipril is hydrolyzed into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. |
|
| FDA_UNII_Code |
WT87C52TJZ |
|
| FULL_SYN |
MOEXIPRIL Moexipril |
|
| Has_Salt_Form | ||
| label |
Moexipril |
|
| Preferred_Name |
Moexipril |
|
| prefixIRI |
Thesaurus:C83967 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0066685 |
|
| subClassOf |