National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Sodium Salicylate

Synonyms

Benzoic acid, 2-hydroxy-, monosodium salt

SODIUM SALICYLATE

Salicylate, sodium

Sodium salicylate

Sodium Salicylate

sodium salicylate

Definitions

The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C834

Accepted_Therapeutic_Use_For

Fever; Inflammatory conditions; Pain

ALT_DEFINITION

A drug that is a type of nonsteroidal anti-inflammatory drug. Sodium salicylate may be tolerated by people who are sensitive to aspirin.

CAS_Registry

54-21-7

Chemical_Formula

C7H5O3.Na

code

C834

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

Contributing_Source

FDA

DEFINITION

The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)

FDA_UNII_Code

WIQ1H85SYP

FULL_SYN

Benzoic acid, 2-hydroxy-, monosodium salt

SODIUM SALICYLATE

Salicylate, sodium

Sodium salicylate

Sodium Salicylate

sodium salicylate

label

Sodium Salicylate

Legacy_Concept_Name

Sodium_Salicylate

NSC_Code

202167

PDQ_Closed_Trial_Search_ID

43094

PDQ_Open_Trial_Search_ID

43094

Preferred_Name

Sodium Salicylate

prefixIRI

ncit:C834

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0037549

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C257

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http://purl.bioontology.org/ontology/RCD/j15.. RCD LOOM
http://purl.bioontology.org/ontology/UATC/N02BA04 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387411000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4018996 VANDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-60360 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.511.390.595.608.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043094 PDQ LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147273 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_9180 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9180 MCO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.410.595.608.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/001586 NDDF LOOM
http://www.co-ode.org/ontologies/galen#SodiumSalicylate GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/9907 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/LP62284-2 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.281.595.608.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.300.595.608.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012980 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D012980 MESH LOOM