Preferred Name

Selenium

Synonyms

Se

selenium

Selenium

SELENIUM

Definitions

A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C825

Accepted_Therapeutic_Use_For

Dandruff; Psoriasis; Seborrheic dermatitis; Tinea capitis; Tinea versicolor

ALT_DEFINITION

A mineral that is needed by the body to stay healthy. It is being studied in the prevention and treatment of some types of cancer. Selenium is a type of antioxidant.

CAS_Registry

7782-49-2

CHEBI_ID

CHEBI:27568

CHEBI:36904

Chemical_Formula

Se

code

C825

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

Contributing_Source

CTRP

FDA

DEFINITION

A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.

Display_Name

Selenium

FDA_UNII_Code

H6241UJ22B

FULL_SYN

Se

selenium

Selenium

SELENIUM

label

Selenium

Legacy_Concept_Name

Selenium

PDQ_Closed_Trial_Search_ID

38725

PDQ_Open_Trial_Search_ID

38725

Preferred_Name

Selenium

prefixIRI

ncit:C825

Semantic_Type

Pharmacologic Substance

Element, Ion, or Isotope

UMLS_CUI

C0036581

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1940

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http://purl.bioontology.org/ontology/MEDDRA/10039918 MEDDRA LOOM
http://purl.obolibrary.org/obo/CHEBI_27568 CHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_27568 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_27568 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_27568 EFO LOOM
http://purl.jp/bio/4/id/200906051759610970 IOBC LOOM
http://www.owl-ontologies.com/Ontology1435740495.owl#Selenium OF LOOM
http://purl.bioontology.org/ontology/CPT/84255 CPT LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036581 MEDLINEPLUS LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/22038003 SNOMEDCT LOOM
http://doe-generated-ontology.com/OntoAD#C0036581 ONTOAD LOOM
http://www.projecthalo.com/aura#Selenium AURA LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000038725 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4020392 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP14283-3 LOINC LOOM
http://scai.fraunhofer.de/CSEO#Selenium CSEO LOOM
http://radlex.org/RID/RID11828 RADLEX LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148196 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007657 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/X7987 RCD LOOM
http://purl.bioontology.org/ontology/NDDF/000864 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012643 RH-MESH LOOM
http://purl.bioontology.org/ontology/CSP/1852-9448 CRISP LOOM
http://bmi.utah.edu/ontologies/hfontology/C0036581 HFO LOOM
http://www.co-ode.org/ontologies/galen#Selenium GALEN LOOM
http://purl.bioontology.org/ontology/npo#NPO_948 NPO LOOM
http://purl.bioontology.org/ontology/phenX/050900 PHENX LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.268.185.850 RH-MESH LOOM
http://localhost/plosthes.2017-1#4558 PLOSTHES LOOM
http://purl.bioontology.org/ontology/RXNORM/9641 RXNORM LOOM
http://id.loc.gov/authorities/subjects/sh85119688 FAST-TOPICAL LOOM
http://www.cea.fr/ontotoxnuc#Selenium ONTOTOXNUC LOOM
http://www.owl-ontologies.com/OntoFood.owl#Selenium FASTO LOOM
http://www.owl-ontologies.com/OntoFood.owl#Selenium DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.578.700 RH-MESH LOOM
http://www.pepathway.org/peo/1.2#Selenium PE-O LOOM
http://purl.bioontology.org/ontology/MESH/D012643 MESH LOOM