National Cancer Institute Thesaurus

Last uploaded: October 28, 2019
Preferred Name

Gamma-Aminobutyric Acid

Synonyms

Piperidic Acid

GABA

Gamma-Aminobutyric Acid

.GAMMA.-AMINOBUTYRIC ACID

4-Aminobutanoic Acid

Definitions

A naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80523

CAS_Registry

56-12-2

CHEBI_ID

CHEBI:16865

Chemical_Formula

C4H9NO2

code

C80523

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.

FDA_UNII_Code

2ACZ6IPC6I

FULL_SYN

Piperidic Acid

GABA

Gamma-Aminobutyric Acid

.GAMMA.-AMINOBUTYRIC ACID

4-Aminobutanoic Acid

label

Gamma-Aminobutyric Acid

Legacy_Concept_Name

Gamma-Aminobutyric_Acid

Preferred_Name

Gamma-Aminobutyric Acid

prefixIRI

ncit:C80523

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0016904

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C687

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http://purl.org/sig/ont/fma/fma84786 FMA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.114.500.350 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.190.350 RH-MESH LOOM
http://purl.obolibrary.org/obo/IMR_0100117 TXPO LOOM
http://purl.org/obo/owlapi/fma#FMA_84786 BIOMODELS LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000191506 NDFRT LOOM
http://purl.obolibrary.org/obo/dinto_DB02530 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 NIFSTD LOOM
http://doe-generated-ontology.com/OntoAD#C0016904 ONTOAD LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Gamma_Aminobutyric_Acid APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Gamma_Aminobutyric_Acid APAONTO LOOM
http://purl.bioontology.org/ontology/RXNORM/4617 RXNORM LOOM
http://localhost/plosthes.2017-1#9838 PLOSTHES LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5309 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D005680 MESH LOOM
http://purl.bioontology.org/ontology/NDDF/006466 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/X807G RCD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/259100002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4034308 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005680 RH-MESH LOOM
http://scai.fraunhofer.de/MSOntology#Gamma_Aminobutyric_Acid MSO LOOM