National Cancer Institute Thesaurus

Last uploaded: June 25, 2019
Preferred Name

Quinolone Antibiotic

Synonyms

Quinolone Antibiotic

Definitions

The basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new derivative compounds with broad antibacterial activity. Both DNA gyrase and topoisomerase IV are targets of quinolones.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C795

code

C795

DEFINITION

The basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new derivative compounds with broad antibacterial activity. Both DNA gyrase and topoisomerase IV are targets of quinolones.

FULL_SYN

Quinolone Antibiotic

label

Quinolone Antibiotic

Legacy_Concept_Name

Quinolone_Antibiotic

Preferred_Name

Quinolone Antibiotic

prefixIRI

ncit:C795

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1882518

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C258

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http://purl.obolibrary.org/obo/CHEBI_86324 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_86324 FYPO LOOM