National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Promethazine

Synonyms

PROMETHAZINE

Promethazine

Definitions

A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine mediated by histamine H1 receptors. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle. In addition, this agent binds to muscarinic receptors, resulting in anticholinergic and antiemetic activities.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C779

CAS_Registry

60-87-7

CHEBI_ID

CHEBI:8461

Chemical_Formula

C17H20N2S

code

C779

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

HemOnc

DEFINITION

A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine mediated by histamine H1 receptors. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle. In addition, this agent binds to muscarinic receptors, resulting in anticholinergic and antiemetic activities.

FDA_UNII_Code

FF28EJQ494

FULL_SYN

PROMETHAZINE

Promethazine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45907

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97704

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66479

label

Promethazine

Legacy Concept Name

Promethazine

NSC Number

30321

Preferred_Name

Promethazine

prefixIRI

Thesaurus:C779

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0033405

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C740

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Delete Mapping To Ontology Source
http://www.case.edu/EpilepsyOntology.owl#Promethazine EPSO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372871004 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB01069 MDM LOOM
http://purl.bioontology.org/ontology/SNMI/C-62820 SNMI LOOM
http://www.case.edu/EpSO.owl#Promethazine MEPO LOOM
http://www.drugbank.ca/drugs/DB01069 FTC LOOM
http://stirdf.jst.go.jp/id/200907048848800824 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.831.690 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011398 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Promethazine GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10179 OCHV LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Promethazine APAONTO LOOM
http://purl.bioontology.org/ontology/RCD/X79JO RCD LOOM
http://purl.bioontology.org/ontology/LNC/LP15006-7 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C779 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0033405 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0012351 OMIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016220 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 MCO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147995 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147995 CIDO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.741.670 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147995 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4019910 VANDF LOOM
http://purl.bioontology.org/ontology/ATC/D04AA10 ATC LOOM
http://purl.bioontology.org/ontology/ATC/R06AD02 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/8745 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D011398 MESH LOOM
http://purl.obolibrary.org/obo/MESH_D011398 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.369.670 RH-MESH LOOM
http://purl.jp/bio/4/id/200906006637143209 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001492 LOINC LOOM