National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Prednisone

Synonyms

Metacortandracin

.delta.1-Cortisone

Prednilonga

Prednisonum

1,2-Dehydrocortisone

1, 2-Dehydrocortisone

Meprosona-F

Deltadehydrocortisone

Deltacortisone

Perrigo Prednisone

Prednisone Intensol

Delta 1-Cortisone

Deltacortene

Liquid Pred

SK-Prednisone

Sk-Prednisone

Prednicen-M

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

Predicorten

Adasone

Cortancyl

Dacortin

DeCortin

Decortisyl

Decorton

Delta-Dome

Deltasone

Deltison

Deltra

Econosone

Lisacort

Meticorten

Ofisolona

Orasone

PRED

PREDNISONE

Panafcort

Panasol-S

Paracort

Predeltin

Predicor

Prednicort

Prednidib

Predniment

Prednisone

Prednitone

Promifen

Rayos

Servisone

Sterapred

prednisone

Definitions

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C770

Accepted_Therapeutic_Use_For

Inflammatory conditions; Allergic conditions; Hematologic conditions; Neoplastic conditions; Autoimmune conditions; Replacement therapy in adrenal insufficiency

ALT_DEFINITION

A drug used to lessen inflammation and lower the body's immune response. It is used with other drugs to treat leukemia and lymphoma and other types of cancer. It is also used alone or with other drugs to prevent or treat many other conditions. These include conditions related to cancer, such as anemia (a low level of red blood cells), allergic reactions, and loss of appetite. Prednisone is a type of therapeutic glucocorticoid.

CAS_Registry

53-03-2

CHEBI_ID

CHEBI:8382

Chemical_Formula

C21H26O5

code

C770

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192234

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183082

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183083

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186328

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186327

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186341

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CTRP

DIPG/DMG

FDA

GDC

HemOnc

OORO

PCDC

DEFINITION

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.

Display_Name

Prednisone

FDA_UNII_Code

VB0R961HZT

FULL_SYN

Metacortandracin

.delta.1-Cortisone

Prednilonga

Prednisonum

1,2-Dehydrocortisone

1, 2-Dehydrocortisone

Meprosona-F

Deltadehydrocortisone

Deltacortisone

Perrigo Prednisone

Prednisone Intensol

Delta 1-Cortisone

Deltacortene

Liquid Pred

SK-Prednisone

Sk-Prednisone

Prednicen-M

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

Predicorten

Adasone

Cortancyl

Dacortin

DeCortin

Decortisyl

Decorton

Delta-Dome

Deltasone

Deltison

Deltra

Econosone

Lisacort

Meticorten

Ofisolona

Orasone

PRED

PREDNISONE

Panafcort

Panasol-S

Paracort

Predeltin

Predicor

Prednicort

Prednidib

Predniment

Prednisone

Prednitone

Promifen

Rayos

Servisone

Sterapred

prednisone

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

Prednisone

Legacy Concept Name

Prednisone

Maps_To

Prednisone

NCI_Drug_Dictionary_ID

42487

NSC Number

10023

PDQ_Closed_Trial_Search_ID

42487

PDQ_Open_Trial_Search_ID

42487

Preferred_Name

Prednisone

prefixIRI

Thesaurus:C770

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0032952

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_8382 CHEBI LOOM
http://purl.bioontology.org/ontology/ATC/A07EA03 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0032952 OCHV LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_ba0a78ca_9692_45e0_a9a6_7c57e2c9e45c STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_ba0a78ca_9692_45e0_a9a6_7c57e2c9e45c CVAO LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0032952 MEDLINEPLUS LOOM
http://purl.obolibrary.org/obo/MESH_D011241 BERO LOOM
http://bmi.utah.edu/ontologies/peontology/C0032952 RAO LOOM
http://purl.bioontology.org/ontology/ATC/H02AB07 ATC LOOM
http://www.limics.fr/ontologies/ontoparonmed#Prednisone ONTOPARON LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8382 NIFSTD LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062944 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP18109-6 LOINC LOOM
http://scai.fraunhofer.de/MSOntology#Prednisone MSO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/116602009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146229 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Prednisone GALEN LOOM
http://purl.bioontology.org/ontology/NDDF/002164 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4017876 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10044 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/8640 RXNORM LOOM
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Prednisone PCAO LOOM
http://purl.bioontology.org/ontology/RCD/fe7.. RCD LOOM
http://www.drugbank.ca/drugs/DB00635 FTC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042487 PDQ LOOM
http://purl.bioontology.org/ontology/MESH/D011241 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018685 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/OMIT_0012204 OMIT LOOM
http://purl.obolibrary.org/obo/NCIT_C770 BERO LOOM
http://purl.jp/bio/4/id/200906008513745017 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/0059-8338 CRISP LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00464 COID LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.432.719.702 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907066508740558 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011241 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00635 MDM LOOM