National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Prednisolone

Synonyms

Lepi-Cortinolo

Meticortelone

1,2-Dehydrohydrocortisone

Delta-Cortef

Di-Adreson-F

Delta-Diona

Kuhlprednon

Delta1-dehydro-hydrocortisone

Deltacortril

Hostacortin H

Predni-Coelin

Cortisolone

Deltidrosol

Longiprednil

prednisolone

Delta-Phoricol

Prednisolone

Linola-H-Fett N

Prednisolonum

Deltasolone

Prednicortelone

Panafcortelone

Metacortandralone

Decaprednil

Pred-Clysma

Precortisyl

Predni-Helvacort

Hydeltrasol

Deltahydrocortisone

(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

Delta- Cortef

Aprednislon

.delta.1-Hydrocortisone

Delta(1)Hydrocortisone

Predeltilone

PREDNISOLONE

Dontisolon D

Adnisolone

Capsoid

Cortalone

Dacortin H

Decortin H

Delta-F

Dhasolone

Estilsona

Fisopred

Frisolona

Gupisone

Hydeltra

Klismacort

Lenisolone

Linola-H N

Meti Derm

Opredsone

Prelone

Prenilone

Sterane

Definitions

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C769

Accepted_Therapeutic_Use_For

Inflammatory conditions; Allergic conditions; Hematologic conditions; Neoplastic conditions; Autoimmune conditions; Replacement therapy in adrenal insufficiency

ALT_DEFINITION

A drug that lessens inflammation and suppresses the body's immune response. It may also kill cancer cells. Prednisolone is used to treat disorders in many organ systems and to treat the symptoms of several types of leukemia and lymphoma. It is also being studied in the treatment of other types of cancer. Prednisolone is a type of therapeutic glucocorticoid.

CAS_Registry

50-24-8

CHEBI_ID

CHEBI:8378

Chemical_Formula

C21H28O5

code

C769

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CTRP

FDA

GDC

HemOnc

DEFINITION

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI04)

Display_Name

Prednisolone

FDA_UNII_Code

9PHQ9Y1OLM

FULL_SYN

Lepi-Cortinolo

Meticortelone

1,2-Dehydrohydrocortisone

Delta-Cortef

Di-Adreson-F

Delta-Diona

Kuhlprednon

Delta1-dehydro-hydrocortisone

Deltacortril

Hostacortin H

Predni-Coelin

Cortisolone

Deltidrosol

Longiprednil

prednisolone

Delta-Phoricol

Prednisolone

Linola-H-Fett N

Prednisolonum

Deltasolone

Prednicortelone

Panafcortelone

Metacortandralone

Decaprednil

Pred-Clysma

Precortisyl

Predni-Helvacort

Hydeltrasol

Deltahydrocortisone

(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

Delta- Cortef

Aprednislon

.delta.1-Hydrocortisone

Delta(1)Hydrocortisone

Predeltilone

PREDNISOLONE

Dontisolon D

Adnisolone

Capsoid

Cortalone

Dacortin H

Decortin H

Delta-F

Dhasolone

Estilsona

Fisopred

Frisolona

Gupisone

Hydeltra

Klismacort

Lenisolone

Linola-H N

Meti Derm

Opredsone

Prelone

Prenilone

Sterane

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1403

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80823

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1202

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1402

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1862

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66461

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66462

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

Prednisolone

Legacy Concept Name

Prednisolone

Maps_To

Prednisolone

NCI_Drug_Dictionary_ID

43296

NSC Number

9120

PDQ_Closed_Trial_Search_ID

43296

PDQ_Open_Trial_Search_ID

43296

Preferred_Name

Prednisolone

prefixIRI

Thesaurus:C769

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0032950

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_8378 OBA LOOM
http://purl.jp/bio/4/id/200906036005597987 IOBC LOOM
http://bmi.utah.edu/ontologies/peontology/C0032950 RAO LOOM
http://purl.bioontology.org/ontology/ATC/A07EA01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.432.769.795 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/8638 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146334 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/S01BA04 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/116601002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/H02AB06 ATC LOOM
http://purl.obolibrary.org/obo/MESH_D011239 BERO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043296 PDQ LOOM
http://stirdf.jst.go.jp/id/200907039479477055 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/A01AC04 ATC LOOM
http://purl.bioontology.org/ontology/CSP/0059-8215 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062945 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP18169-0 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/S02BA03 ATC LOOM
https://go.drugbank.com/drugs/DB00860 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10042 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/R01AD02 ATC LOOM
http://webprotege.stanford.edu/RMLTPoYQg83oLCbnC9p0or COPDO LOOM
http://purl.bioontology.org/ontology/ATC/D07AA03 ATC LOOM
http://purl.bioontology.org/ontology/ATC/C05AA04 ATC LOOM
http://purl.obolibrary.org/obo/NCIT_C769 BERO LOOM
http://purl.bioontology.org/ontology/VANDF/4017988 VANDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018695 PMAPP-PMO LOOM
http://scai.fraunhofer.de/MSOntology#Prednisolone MSO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0032950 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0012203 OMIT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146334 ODAE LOOM
http://www.drugbank.ca/drugs/DB00860 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 ODNAE LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Prednisolone APAONTO LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00183 OCIMIDO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011239 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D011239 MESH LOOM
http://purl.bioontology.org/ontology/ATC/S03BA02 ATC LOOM
http://purl.bioontology.org/ontology/ATC/S01CB02 ATC LOOM
http://www.co-ode.org/ontologies/galen#Prednisolone GALEN LOOM
http://purl.bioontology.org/ontology/NDDF/002155 NDDF LOOM
http://purl.bioontology.org/ontology/ATC/D07XA02 ATC LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00852 COID LOOM