National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Cangrelor

Synonyms

AR-C69931MX

CANGRELOR

Cangrelor

Definitions

An inhibitor of the platelet adenosine diphosphate (ADP) P2Y12 receptor (P2Y12R), with antiplatelet activity. Upon administration, cangrelor selectively and reversibly binds to P2Y12R, and blocks the platelet signaling pathway. This inhibits the activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76395

CAS_Registry

163706-06-7

Chemical_Formula

C17H25Cl2F3N5O12P3S2

code

C76395

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

HemOnc

DEFINITION

An inhibitor of the platelet adenosine diphosphate (ADP) P2Y12 receptor (P2Y12R), with antiplatelet activity. Upon administration, cangrelor selectively and reversibly binds to P2Y12R, and blocks the platelet signaling pathway. This inhibits the activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation.

FDA_UNII_Code

6AQ1Y404U7

FULL_SYN

AR-C69931MX

CANGRELOR

Cangrelor

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76396

label

Cangrelor

Legacy Concept Name

Cangrelor

Preferred_Name

Cangrelor

prefixIRI

Thesaurus:C76395

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1121991

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190801

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