loading...| Preferred Name |
Abciximab |
|
| Synonyms |
Chimeric 7E3 Fab ABCIXIMAB Abciximab MoAb 7E3 ReoPro |
|
| Definitions |
A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76128 |
|
| Accepted_Therapeutic_Use_For |
as an adjunct to aspirin and heparin for the prevention of acute cardiac ischemic complications |
|
| CAS_Registry |
143653-53-6 |
|
| code |
C76128 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA HemOnc |
|
| DEFINITION |
A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation. |
|
| FDA_UNII_Code |
X85G7936GV |
|
| FULL_SYN |
Chimeric 7E3 Fab ABCIXIMAB Abciximab MoAb 7E3 ReoPro |
|
| label |
Abciximab |
|
| Legacy Concept Name |
Abciximab |
|
| Preferred_Name |
Abciximab |
|
| prefixIRI |
Thesaurus:C76128 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance Immunologic Factor |
|
| UMLS_CUI |
C0288672 |
|
| subClassOf |