National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pipobroman

Synonyms

Amedel

PIPOBROMAN

Pipobroman

Vercyte

Definitions

A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C750

CAS_Registry

54-91-1

Chemical_Formula

C10H16Br2N2O2

code

C750

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

FDA

GDC

HemOnc

DEFINITION

A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death.

FDA_UNII_Code

6Q99RDT97R

FULL_SYN

Amedel

PIPOBROMAN

Pipobroman

Vercyte

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

Pipobroman

Legacy Concept Name

Pipobroman

Maps_To

Pipobroman

NSC Number

25154

Preferred_Name

Pipobroman

prefixIRI

Thesaurus:C750

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0031965

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1590

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