National Cancer Institute Thesaurus

Last uploaded: October 28, 2019
Preferred Name

Pipobroman

Synonyms

Pipobroman

Amedel

PIPOBROMAN

Vercyte

Definitions

A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C750

CAS_Registry

54-91-1

Chemical_Formula

C10H16Br2N2O2

code

C750

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

Contributing_Source

FDA

DEFINITION

A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death.

FDA_UNII_Code

6Q99RDT97R

FULL_SYN

Pipobroman

Amedel

PIPOBROMAN

Vercyte

label

Pipobroman

Legacy_Concept_Name

Pipobroman

NSC_Code

25154

Preferred_Name

Pipobroman

prefixIRI

ncit:C750

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0031965

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1590

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.606.773 RH-MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB00236 DINTO LOOM
http://purl.bioontology.org/ontology/MESH/D010885 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/8347 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010885 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/002099 NDDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-781B0 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_8242 CHEBI LOOM
http://purl.bioontology.org/ontology/UATC/L01AX02 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/24823004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4018739 VANDF LOOM
http://purl.obolibrary.org/obo/DRON_00011385 DRON LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147043 NDFRT LOOM