Preferred Name |
Dabigatran |
|
Synonyms |
DABIGATRAN Dabigatran |
|
Definitions |
A benzimidazole and direct thrombin inhibitor, with anticoagulant activity. Upon administration, dabigatran reversibly binds to and inhibits the activity of thrombin, a serine protease that converts fibrinogen into fibrin. This disrupts the coagulation cascade and inhibits the formation of blood clots. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73224 |
|
CAS_Registry |
211914-51-1 |
|
Chemical_Formula |
C25H25N7O3 |
|
code |
C73224 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
Contributing_Source |
CTRP FDA HemOnc |
|
DEFINITION |
A benzimidazole and direct thrombin inhibitor, with anticoagulant activity. Upon administration, dabigatran reversibly binds to and inhibits the activity of thrombin, a serine protease that converts fibrinogen into fibrin. This disrupts the coagulation cascade and inhibits the formation of blood clots. |
|
Display_Name |
Dabigatran |
|
FDA_UNII_Code |
I0VM4M70GC |
|
FULL_SYN |
DABIGATRAN Dabigatran |
|
Has_Salt_Form | ||
label |
Dabigatran |
|
Legacy Concept Name |
Dabigatran |
|
Preferred_Name |
Dabigatran |
|
prefixIRI |
Thesaurus:C73224 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C2348066 |
|
subClassOf |