National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Deferiprone

Synonyms

Deferiprone

4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl-

DEFERIPRONE

DN-180-01-AF

APO-066

CP20

Ferriprox

Definitions

An orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1 (ligand:iron) molar ratio. By binding to iron, deferiprone is able to remove excess iron from the body.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73030

Accepted_Therapeutic_Use_For

Hemosiderosis

CAS_Registry

30652-11-0

Chemical_Formula

C7H9NO2

code

C73030

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

HemOnc

DEFINITION

An orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1 (ligand:iron) molar ratio. By binding to iron, deferiprone is able to remove excess iron from the body.

FDA_UNII_Code

2BTY8KH53L

FULL_SYN

Deferiprone

4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl-

DEFERIPRONE

DN-180-01-AF

APO-066

CP20

Ferriprox

label

Deferiprone

Legacy Concept Name

Deferiprone

NCI_Drug_Dictionary_ID

761978

PDQ_Closed_Trial_Search_ID

761978

PDQ_Open_Trial_Search_ID

761978

Preferred_Name

Deferiprone

prefixIRI

Thesaurus:C73030

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0043832

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C360

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