loading...| Preferred Name |
Tigecycline |
|
| Synonyms |
Tigecycline TIGECYCLINE Tygacil |
|
| Definitions |
A broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This prevents the incorporation of amino acid residues into the elongating peptide chain, inhibiting protein synthesis and eventually bacterial cell growth. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72865 |
|
| Accepted_Therapeutic_Use_For |
Community-Acquired Bacterial Pneumonia |
|
| CAS_Registry |
220620-09-7 |
|
| CHEBI_ID |
CHEBI:149836 |
|
| Chemical_Formula |
C29H39N5O8 |
|
| code |
C72865 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This prevents the incorporation of amino acid residues into the elongating peptide chain, inhibiting protein synthesis and eventually bacterial cell growth. |
|
| FDA_UNII_Code |
70JE2N95KR |
|
| FULL_SYN |
Tigecycline TIGECYCLINE Tygacil |
|
| label |
Tigecycline |
|
| Legacy Concept Name |
Tigecycline |
|
| Preferred_Name |
Tigecycline |
|
| prefixIRI |
Thesaurus:C72865 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C1260298 |
|
| subClassOf |