Preferred Name |
Papaverine |
|
Synonyms |
Cerebid Cerespan PAPAVERINE Papaverine Pavabid Pavacap Pavatym Robaxapap |
|
Definitions |
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. (NCI04) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C726 |
|
Accepted_Therapeutic_Use_For |
Ischemia, cerebral and peripheral |
|
CAS_Registry |
58-74-2 |
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CHEBI_ID |
CHEBI:28241 |
|
Chemical_Formula |
C20H21NO4 |
|
code |
C726 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
Contributing_Source |
CTRP FDA |
|
DEFINITION |
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. (NCI04) |
|
Display_Name |
Papaverine |
|
FDA_UNII_Code |
DAA13NKG2Q |
|
FULL_SYN |
Cerebid Cerespan PAPAVERINE Papaverine Pavabid Pavacap Pavatym Robaxapap |
|
Has_Salt_Form | ||
label |
Papaverine |
|
Legacy Concept Name |
Papaverine |
|
NCI_Drug_Dictionary_ID |
39545 |
|
NSC Number |
136630 |
|
PDQ_Closed_Trial_Search_ID |
39545 |
|
PDQ_Open_Trial_Search_ID |
39545 |
|
Preferred_Name |
Papaverine |
|
prefixIRI |
Thesaurus:C726 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0030350 |
|
subClassOf |