National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Clinical Trial

Synonyms

Trial

Clinical Trials, Unspecified

Clinical Trials

Clinical Trial

clinical trial

Definitions

A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71104

ALT_DEFINITION

A type of research study that tests how well new medical approaches work in people. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease.

A research investigation involving human subjects that is designed to answer specific questions about the safety and efficacy of a biomedical intervention (drug, treatment, device) or new ways of using a known drug, treatment, or device). NOTE: NIH Office of Science Policy further specifies that a clinical trial is a type of research study that prospectively assigns subjects to interventions, and the EU clinical trial regulations set forth 3 specific conditions, any one of which qualifies a study as a clinical trial. These conditions include applying diagnostic or monitoring procedures not used in normal clinical practice to subjects. [after ICH E6 [R2], EU CTR 2014] See also clinical study, clinical investigation.

1) A research investigation involving human subjects that is designed to answer specific questions about the safety and efficacy of a biomedical intervention (drug, treatment, device) or new ways of using a known drug, treatment, or device). 2) A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes.(1. modified from ICH E6 Glossary, Directive 2001/20/EC. 2. NIH revised definition 2015) (CDISC Glossary)

code

C71104

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132298

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67497

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132310

Contributing_Source

CDISC

CDISC-GLOSS

DEFINITION

A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes.

FULL_SYN

Trial

Clinical Trials, Unspecified

Clinical Trials

Clinical Trial

clinical trial

label

Clinical Trial

Legacy_Concept_Name

Clinical_Trial_Generic

Preferred_Name

Clinical Trial

prefixIRI

ncit:C71104

Semantic_Type

Research Activity

UMLS_CUI

C0008976

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15206

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http://ontologies.dbmi.pitt.edu/edda/StudyDesigns.owl#clinical_trial EDDA LOOM
http://purl.bioontology.org/ontology/CSP/0690-6917 CRISP LOOM
http://semanticscience.org/resource/SIO_001000 ORTH LOOM
http://semanticscience.org/resource/SIO_001000 BIOMO LOOM
http://semanticscience.org/resource/SIO_001000 SIO LOOM
http://purl.bioontology.org/ontology/MESH/D016430 NLN LOOM
http://purl.bioontology.org/ontology/MESH/D016430 MESH LOOM
http://edda.dbmi.pitt.edu/ontologies/StudyDesigns.owl#clinical_trial DIKB LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C1096775 OCHV LOOM
http://purl.obolibrary.org/obo/ICO_0000065 ICO LOOM
http://epoch.stanford.edu/ClinicalTrialOntology.owl#ClinicalTrial CTONT LOOM
http://w3id.org/biolink/vocab/ClinicalTrial BLM LOOM
http://semanticscience.org/resource/ClinicalTrial CHEAR LOOM
http://semanticscience.org/resource/ClinicalTrial HASCO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008976 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/110465008 SNOMEDCT LOOM
http://www.ifomis.org/acgt/1.0#ClinicalTrial ACGT-MO LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00001060 CSEO LOOM
http://chem.deri.ie/granatum#ClinicalTrial CANCO LOOM
http://purl.jp/bio/4/id/200906097612464561 IOBC LOOM
http://purl.bioontology.org/ontology/HL7/C0008976 HL7 LOOM
http://purl.obolibrary.org/obo/ERO_0000016 VIVO-ISF LOOM
http://purl.obolibrary.org/obo/ERO_0000016 OGSF LOOM
http://purl.obolibrary.org/obo/ERO_0000016 VIVO LOOM
http://purl.obolibrary.org/obo/ERO_0000016 ERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#V03.200 RH-MESH LOOM
http://www.w3.org/2001/sw/hcls/ns/transmed/TMO_0032 TMO LOOM
http://purl.obolibrary.org/obo/dinto_004360 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016430 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Clinical_Trial_Generic SYN LOOM
http://www.loria.fr/~coulet/ontology/sopharm/version2.1/#SOPHARM_60000 HUPSON LOOM
http://purl.obolibrary.org/obo/NCIT_C71104 PREMEDONTO LOOM
http://purl.bioontology.org/ontology/HL7/C1552009 HL7 LOOM
http://www.co-ode.org/ontologies/ont.owl#Clinical_trial CTO LOOM
http://purl.obolibrary.org/obo/OPMI_0004507 OPMI LOOM
http://purl.obolibrary.org/obo/OPMI_0004507 OPMI LOOM