National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Novobiocin

Synonyms

NOVOBIOCIN

Novobiocin

novobiocin

Definitions

An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other aminocoumarin antibiotics, inhibits bacterial DNA synthesis by targeting at the bacteria DNA gyrase and the related enzyme DNA topoisomerase IV. This antibiotic was used to treat infections by gram-positive bacteria.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C705

ALT_DEFINITION

An antibiotic drug used to treat infection.

CAS_Registry

303-81-1

CHEBI_ID

CHEBI:28368

Chemical_Formula

C31H36N2O11

code

C705

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other aminocoumarin antibiotics, inhibits bacterial DNA synthesis by targeting at the bacteria DNA gyrase and the related enzyme DNA topoisomerase IV. This antibiotic was used to treat infections by gram-positive bacteria.

FDA_UNII_Code

17EC19951N

FULL_SYN

NOVOBIOCIN

Novobiocin

novobiocin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81448

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66247

label

Novobiocin

Legacy Concept Name

Novobiocin

NCI_Drug_Dictionary_ID

39195

NSC Number

2382

PDQ_Closed_Trial_Search_ID

39195

PDQ_Open_Trial_Search_ID

39195

Preferred_Name

Novobiocin

prefixIRI

Thesaurus:C705

Semantic_Type

Organic Chemical

Pharmacologic Substance

Antibiotic

UMLS_CUI

C0028458

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C258

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_28368 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 CHEBI LOOM
http://purl.obolibrary.org/obo/ARO_3000111 ARO LOOM
http://purl.bioontology.org/ontology/VANDF/4019861 VANDF LOOM
http://purl.obolibrary.org/obo/MESH_D009675 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0010694 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.150.446.139.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8792 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/C-52260 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D09.408.554 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/90220005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007486 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/7538 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.830.219.446.139.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D009675 MESH LOOM
http://purl.obolibrary.org/obo/UPa_UPC05080 UPA LOOM
http://purl.obolibrary.org/obo/dinto_DB01051 DINTO LOOM
http://purl.bioontology.org/ontology/CSP/0203-4078 CRISP LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147947 NDFRT LOOM
http://purl.obolibrary.org/obo/NCIT_C705 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_28368 MCO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009675 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017669 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028458 OCHV LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039195 PDQ LOOM
https://go.drugbank.com/drugs/DB01051 MDM LOOM
http://purl.bioontology.org/ontology/NDDF/002761 NDDF LOOM
http://purl.jp/bio/4/id/200906073421967354 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP16168-4 LOINC LOOM
http://stirdf.jst.go.jp/id/200907058571761660 IOBC LOOM