National Cancer Institute Thesaurus

Last uploaded: March 26, 2019
Preferred Name

Norgestrel

Synonyms

Norgestrel

Ovrette

NORGESTREL

(+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one

Wy-3707

Neogest

(17alpha)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one

Definitions

A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C703

Accepted_Therapeutic_Use_For

Oral contraception

CAS_Registry

6533-00-2

CHEBI_ID

CHEBI:7630

CHEBI:50901

Chemical_Formula

C21H28O2

code

C703

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

FDA

DEFINITION

A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04)

Display_Name

Norgestrel

FDA_UNII_Code

3J8Q1747Z2

FULL_SYN

Norgestrel

Ovrette

NORGESTREL

(+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one

Wy-3707

Neogest

(17alpha)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one

label

Norgestrel

Legacy_Concept_Name

Norgestrel

PDQ_Closed_Trial_Search_ID

39310

PDQ_Open_Trial_Search_ID

39310

Preferred_Name

Norgestrel

prefixIRI

ncit:C703

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0028368

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C776

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http://www.co-ode.org/ontologies/galen#Norgestrel GALEN LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7630 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/126106007 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.668.651.693.762 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D009644 MESH LOOM
http://stirdf.jst.go.jp/id/200907012691122431 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/7518 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009644 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4018023 VANDF LOOM
http://purl.jp/bio/4/id/200906097095929362 IOBC LOOM
http://purl.jp/bio/4/id/200906097095929362 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146367 NDFRT LOOM
http://id.loc.gov/authorities/subjects/sh85092414 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/NDDF/001303 NDDF LOOM
http://purl.bioontology.org/ontology/NDDF/001325 NDDF LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004733 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004733 DMTO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039310 PDQ LOOM