loading...| Preferred Name |
Norgestrel |
|
| Synonyms |
(17alpha)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one (+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one NORGESTREL Neogest Norgestrel Ovrette Wy-3707 |
|
| Definitions |
A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C703 |
|
| Accepted_Therapeutic_Use_For |
Oral contraception |
|
| CAS_Registry |
6533-00-2 |
|
| CHEBI_ID |
CHEBI:50901 CHEBI:7630 |
|
| Chemical_Formula |
C21H28O2 |
|
| code |
C703 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
CTRP FDA GDC |
|
| DEFINITION |
A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04) |
|
| Display_Name |
Norgestrel |
|
| FDA_UNII_Code |
3J8Q1747Z2 |
|
| FULL_SYN |
(17alpha)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one (+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one NORGESTREL Neogest Norgestrel Ovrette Wy-3707 |
|
| Is_Value_For_GDC_Property | ||
| label |
Norgestrel |
|
| Legacy Concept Name |
Norgestrel |
|
| Maps_To |
Norgestrel |
|
| NCI_Drug_Dictionary_ID |
39310 |
|
| PDQ_Closed_Trial_Search_ID |
39310 |
|
| PDQ_Open_Trial_Search_ID |
39310 |
|
| Preferred_Name |
Norgestrel |
|
| prefixIRI |
Thesaurus:C703 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0028368 |
|
| subClassOf |