loading...| Preferred Name |
Eicosapentaenoic Acid |
|
| Synonyms |
Icosapentaenoic Acid Fatty Acid 20:5 Timnodonic Acid All cis-5,8,11,14,17-Eicosapentaenoic Acid Eicosapentaenoic Acid EPA IPA |
|
| Definitions |
An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67080 |
|
| ALT_DEFINITION |
A class of polyunsaturated fatty acids with 20 carbons and 5 double bonds. |
|
| CAS_Registry |
25378-27-2 |
|
| CHEBI_ID |
CHEBI:36006 |
|
| Chemical_Formula |
C20H30O2 |
|
| code |
C67080 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CRCH CTRP GDC |
|
| DEFINITION |
An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes. |
|
| Display_Name |
Eicosapentaenoic Acid |
|
| Essential_Fatty_Acid |
Y |
|
| FULL_SYN |
Icosapentaenoic Acid Fatty Acid 20:5 Timnodonic Acid All cis-5,8,11,14,17-Eicosapentaenoic Acid Eicosapentaenoic Acid EPA IPA |
|
| Has_Target | ||
| INFOODS |
F20D5 |
|
| Is_Value_For_GDC_Property | ||
| label |
Eicosapentaenoic Acid |
|
| Legacy Concept Name |
Eicosapentaenoic_Acid |
|
| Macronutrient |
Y |
|
| Maps_To |
Eicosapentaenoic Acid |
|
| NCI_Drug_Dictionary_ID |
537376 |
|
| Nutrient |
Y |
|
| PDQ_Closed_Trial_Search_ID |
537376 |
|
| PDQ_Open_Trial_Search_ID |
537376 |
|
| Preferred_Name |
Eicosapentaenoic Acid |
|
| prefixIRI |
Thesaurus:C67080 |
|
| Semantic_Type |
Organic Chemical |
|
| UMLS_CUI |
C0000545 |
|
| Unit |
g |
|
| subClassOf |