National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Morphine Sulfate

Synonyms

MORPHINE SULFATE

morphine sulfate

Oramorph SR

Morphine Sulfate

Avinza

Infumorph

Kadian

MS Contin

MSir

Morphine

Oramorph

Roxanol

Statex SR

Definitions

The sulfate salt of morphine, an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent has widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C669

ALT_DEFINITION

A drug used to treat moderate to severe pain. It binds to opioid receptors in the central nervous system and some other tissues. Morphine sulfate is made from opium. It is a type of opiate and a type of analgesic agent.

CAS_Registry

6211-15-0

64-31-3

CHEBI_ID

CHEBI:50731

CHEBI:7003

Chemical_Formula

2C17H19NO3.5H2O.H2SO4

code

C669

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156953

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CPTAC

CTRP

FDA

DEFINITION

The sulfate salt of morphine, an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent has widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction.

Display_Name

Morphine Sulfate

FDA_UNII_Code

X3P646A2J0

FULL_SYN

MORPHINE SULFATE

morphine sulfate

Oramorph SR

Morphine Sulfate

Avinza

Infumorph

Kadian

MS Contin

MSir

Morphine

Oramorph

Roxanol

Statex SR

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62051

label

Morphine Sulfate

Legacy Concept Name

Morphine

NCI_Drug_Dictionary_ID

41804

NSC Number

11441

PDQ_Closed_Trial_Search_ID

41804

PDQ_Open_Trial_Search_ID

41804

Preferred_Name

Morphine Sulfate

prefixIRI

Thesaurus:C669

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0722208

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67413

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