National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Propiomazine

Synonyms

PROPIOMAZINE

Propiomazine

Definitions

A phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66486

CAS_Registry

362-29-8

CHEBI_ID

CHEBI:8491

Chemical_Formula

C20H24N2OS

code

C66486

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.

FDA_UNII_Code

242Z0PM79Y

FULL_SYN

PROPIOMAZINE

Propiomazine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66487

label

Propiomazine

Legacy Concept Name

Propiomazine

Preferred_Name

Propiomazine

prefixIRI

Thesaurus:C66486

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0033473

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29710

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