loading...| Preferred Name |
Nebivolol |
|
| Synonyms |
Bystolic NEBIVOLOL Nebivolol |
|
| Definitions |
A beta-1 adrenergic receptor antagonist with antihypertensive and vasodilatory activity. Nebivolol binds to and blocks the beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, nebivolol potentiates nitric oxide (NO), thereby relaxing vascular smooth muscle and exerting a vasodilatory effect. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66221 |
|
| Accepted_Therapeutic_Use_For |
Hypertension |
|
| CAS_Registry |
118457-14-0 |
|
| CHEBI_ID |
CHEBI:64022 |
|
| Chemical_Formula |
C22H25F2NO4 |
|
| code |
C66221 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A beta-1 adrenergic receptor antagonist with antihypertensive and vasodilatory activity. Nebivolol binds to and blocks the beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, nebivolol potentiates nitric oxide (NO), thereby relaxing vascular smooth muscle and exerting a vasodilatory effect. |
|
| FDA_UNII_Code |
030Y90569U |
|
| FULL_SYN |
Bystolic NEBIVOLOL Nebivolol |
|
| Has_Salt_Form | ||
| label |
Nebivolol |
|
| Legacy Concept Name |
Nebivolol |
|
| NCI_Drug_Dictionary_ID |
812554 |
|
| Preferred_Name |
Nebivolol |
|
| prefixIRI |
Thesaurus:C66221 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0068475 |
|
| subClassOf |