National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Methyltestosterone

Synonyms

Methyltestosteronum

Testotonic B

(17Beta)-17-hydroxy-17-methylandrost-4-en-3-one

17-Methyltestosterone

Neohombreol M

Orchisterone-M

Glosso-Sterandryl

Methyltestosterone

Oreton Methyl

Oreton methyl

METHYLTESTOSTERONE

17 Alpha-methyl-delta4-androsten-17beta-ol-4-one

Android

Eldec

Ero Test

Estratest

Malogen

Metandren

Methitest

Testomet

Testovis

Testred

Virilon

Definitions

A methylated synthetic androgen receptor agonist with anabolic effects. Methyltestosterone, mimicking testosterone, binds to cytosolic androgen receptors, and the subsequent nuclear transfer of the ligand-receptor complex induces transcription initiation of androgen responsive genes. The gene products are responsible for normal growth and development of male sex organs and secondary sex characteristics. The agent also causes retention of nitrogen, sodium, potassium, phosphorus, as well as calcium.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C648

CAS_Registry

58-18-4

CHEBI_ID

CHEBI:27436

Chemical_Formula

C20H30O2

code

C648

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

FDA

GDC

DEFINITION

A methylated synthetic androgen receptor agonist with anabolic effects. Methyltestosterone, mimicking testosterone, binds to cytosolic androgen receptors, and the subsequent nuclear transfer of the ligand-receptor complex induces transcription initiation of androgen responsive genes. The gene products are responsible for normal growth and development of male sex organs and secondary sex characteristics. The agent also causes retention of nitrogen, sodium, potassium, phosphorus, as well as calcium.

FDA_UNII_Code

V9EFU16ZIF

FULL_SYN

Methyltestosteronum

Testotonic B

(17Beta)-17-hydroxy-17-methylandrost-4-en-3-one

17-Methyltestosterone

Neohombreol M

Orchisterone-M

Glosso-Sterandryl

Methyltestosterone

Oreton Methyl

Oreton methyl

METHYLTESTOSTERONE

17 Alpha-methyl-delta4-androsten-17beta-ol-4-one

Android

Eldec

Ero Test

Estratest

Malogen

Metandren

Methitest

Testomet

Testovis

Testred

Virilon

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

Methyltestosterone

Legacy Concept Name

Methyltestosterone

Maps_To

Methyltestosterone

NSC Number

9701

Preferred_Name

Methyltestosterone

prefixIRI

Thesaurus:C648

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0025826

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C243

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http://purl.obolibrary.org/obo/CHEBI_27436 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 HSPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_27436 CHEBI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/126161000 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008777 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.054.079.429.824.664 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/G03BA02 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018538 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/MESH/D008777 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8066 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025826 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C648 BERO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062997 LOINC LOOM
http://purl.jp/bio/4/id/200906034294794407 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/G03EK01 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4017433 VANDF LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039268 PDQ LOOM
http://purl.obolibrary.org/obo/MESH_D008777 BERO LOOM
https://go.drugbank.com/drugs/DB06710 MDM LOOM
http://purl.bioontology.org/ontology/LNC/LP15737-7 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145821 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907011154614062 IOBC LOOM
http://www.drugbank.ca/drugs/DB06710 FTC LOOM
http://purl.bioontology.org/ontology/RXNORM/6904 RXNORM LOOM
http://purl.obolibrary.org/obo/OMIT_0009834 OMIT LOOM