loading...| Preferred Name |
Methoxsalen |
|
| Synonyms |
8-Methoxypsoralen Puvasoralen XANTHOTOXIN 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one Xanthotoxin Deltasoralen METHOXSALEN Oxsoralen-Ultra methoxsalen Methoxypsoralen Methoxsalen 8-MOP Ammoidin Dermox Geralen Geroxalen Meladinina Meladinine Metoxaleno Mopsoralen Oxsoralen Ultramop Uvadex |
|
| Definitions |
A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C643 |
|
| Accepted_Therapeutic_Use_For |
Cutaneous T-cell lymphoma; psoriasis; vitiligo |
|
| ALT_DEFINITION |
A drug used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell lymphoma. It is also being studied in the treatment of graft-versus-host disease. It belongs to the family of drugs called psoralens and furocoumarins. |
|
| CAS_Registry |
298-81-7 |
|
| CHEBI_ID |
CHEBI:18358 |
|
| Chemical_Formula |
C12H8O4 |
|
| code |
C643 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
CTRP FDA GDC HemOnc |
|
| DEFINITION |
A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. (NCI04) |
|
| Display_Name |
Methoxsalen |
|
| FDA_UNII_Code |
U4VJ29L7BQ |
|
| FULL_SYN |
8-Methoxypsoralen Puvasoralen XANTHOTOXIN 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one Xanthotoxin Deltasoralen METHOXSALEN Oxsoralen-Ultra methoxsalen Methoxypsoralen Methoxsalen 8-MOP Ammoidin Dermox Geralen Geroxalen Meladinina Meladinine Metoxaleno Mopsoralen Oxsoralen Ultramop Uvadex |
|
| Is_Value_For_GDC_Property | ||
| label |
Methoxsalen |
|
| Legacy Concept Name |
Methoxsalen |
|
| Maps_To |
Methoxsalen |
|
| NCI_Drug_Dictionary_ID |
39499 |
|
| NSC Number |
45923 |
|
| PDQ_Closed_Trial_Search_ID |
39499 |
|
| PDQ_Open_Trial_Search_ID |
39499 |
|
| Preferred_Name |
Methoxsalen |
|
| prefixIRI |
Thesaurus:C643 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0025684 |
|
| subClassOf |