National Cancer Institute Thesaurus

Last uploaded: November 25, 2019
Preferred Name

Dendrimer

Synonyms

Cascade Molecule

Dendrimer

Definitions

A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62363

CHEBI_ID

CHEBI:51338

CHEBI:61483

code

C62363

DEFINITION

A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.

FULL_SYN

Cascade Molecule

Dendrimer

label

Dendrimer

Legacy_Concept_Name

Dendrimer

Preferred_Name

Dendrimer

prefixIRI

ncit:C62363

Semantic_Type

Chemical Viewed Structurally

UMLS_CUI

C1563732

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48803

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http://purl.bioontology.org/ontology/npo#NPO_735 ENM LOOM
http://purl.bioontology.org/ontology/npo#NPO_735 NPO LOOM
http://purl.jp/bio/4/id/200906007848981720 IOBC LOOM