National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Oxacillin

Synonyms

OXACILLIN

Oxacillin

Definitions

A semisynthetic penicillinase-resistant and acid-stable penicillin with an antimicrobial activity. Oxacillin binds to penicillin-binding proteins in the bacterial cell wall, thereby blocking the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to inhibition of cell growth and causes cell lysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62063

CAS_Registry

66-79-5

CHEBI_ID

CHEBI:7809

Chemical_Formula

C19H19N3O5S

code

C62063

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A semisynthetic penicillinase-resistant and acid-stable penicillin with an antimicrobial activity. Oxacillin binds to penicillin-binding proteins in the bacterial cell wall, thereby blocking the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to inhibition of cell growth and causes cell lysis.

Display_Name

Oxacillin

FDA_UNII_Code

UH95VD7V76

FULL_SYN

OXACILLIN

Oxacillin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C720

label

Oxacillin

Legacy Concept Name

Oxacillin_Base

Preferred_Name

Oxacillin

prefixIRI

Thesaurus:C62063

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0029983

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_7809 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 CHEBI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147953 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7809 NIFSTD LOOM
http://purl.obolibrary.org/obo/ARO_0000056 ARO LOOM
http://purl.obolibrary.org/obo/MESH_D010068 BERO LOOM
https://go.drugbank.com/drugs/DB00713 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0029983 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP16206-2 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9135 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Oxacillin GALEN LOOM
http://stirdf.jst.go.jp/id/200907030727098182 IOBC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015919 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008465 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.108.750.625 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.260.825.625 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/J01CF04 ATC LOOM
http://purl.obolibrary.org/obo/NCIT_C62063 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010068 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-54460 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4019867 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.750.625 RH-MESH LOOM
http://purl.jp/bio/4/id/200906036466210669 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D010068 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372868007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/7773 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.084.737.625 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.750.625 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/004834 NDDF LOOM
http://purl.obolibrary.org/obo/OMIT_0011073 OMIT LOOM