National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Norethindrone

Synonyms

Norethindrone

NORETHINDRONE

Norethisterone

Camila

Errin

Micronor

Norlutin

Definitions

A synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. Norethindrone binds to the progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. This leads to an alteration in protein synthesis and results in an inhibition of LH release. Consequently, it inhibits ovulation and changes the normal cycle of cervical mucus and endometrium.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62059

CAS_Registry

68-22-4

CHEBI_ID

CHEBI:7627

Chemical_Formula

C20H26O2

code

C62059

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. Norethindrone binds to the progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. This leads to an alteration in protein synthesis and results in an inhibition of LH release. Consequently, it inhibits ovulation and changes the normal cycle of cervical mucus and endometrium.

FDA_UNII_Code

T18F433X4S

FULL_SYN

Norethindrone

NORETHINDRONE

Norethisterone

Camila

Errin

Micronor

Norlutin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C702

label

Norethindrone

Legacy Concept Name

Norethindrone_Base

Preferred_Name

Norethindrone

prefixIRI

Thesaurus:C62059

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0028356

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C776

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