National Cancer Institute Thesaurus

Last uploaded: July 29, 2019
Preferred Name

Succinylcholine

Synonyms

SUCCINYLCHOLINE

Succinylcholine

Definitions

A quaternary ammonium compound and depolarizing agent with short-term muscle relaxant properties. Succinylcholine binds to nicotinic receptors at the neuromuscular junction and opening the ligand-gated channels in the same way as acetylcholine, resulting in depolarization and inhibition of neuromuscular transmission. Depolarization may be prolonged due to succinylcholine's resistance to acetylcholinesterases thereby leading to disorganized muscle contraction followed by skeletal muscle relaxation and flaccid paralysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61955

CAS_Registry

306-40-1

CHEBI_ID

CHEBI:45652

Chemical_Formula

C14H30N2O4

code

C61955

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A quaternary ammonium compound and depolarizing agent with short-term muscle relaxant properties. Succinylcholine binds to nicotinic receptors at the neuromuscular junction and opening the ligand-gated channels in the same way as acetylcholine, resulting in depolarization and inhibition of neuromuscular transmission. Depolarization may be prolonged due to succinylcholine's resistance to acetylcholinesterases thereby leading to disorganized muscle contraction followed by skeletal muscle relaxation and flaccid paralysis.

FDA_UNII_Code

J2R869A8YF

FULL_SYN

SUCCINYLCHOLINE

Succinylcholine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47730

label

Succinylcholine

Legacy_Concept_Name

Succinylcholine

Preferred_Name

Succinylcholine

prefixIRI

ncit:C61955

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0038627

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29696

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http://purl.bioontology.org/ontology/VANDF/4019935 VANDF LOOM
http://www.co-ode.org/ontologies/galen#Succinylcholine GALEN LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003240 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/D013390 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372724004 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.337.759.875 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP15143-8 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45652 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013390 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00202 FTC LOOM
http://purl.bioontology.org/ontology/SNMI/C-68710 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148020 NDFRT LOOM
http://purl.jp/bio/4/id/200906059423052989 IOBC LOOM
http://purl.jp/bio/4/id/200906059423052989 IOBC LOOM
http://purl.jp/bio/4/id/200906059423052989 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.675.276.232.780 RH-MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Succinylcholine APAONTO LOOM
http://purl.bioontology.org/ontology/RXNORM/10154 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.877.883.333.780 RH-MESH LOOM