National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Sotalol

Synonyms

SOTALOL

Sotalol

Definitions

An ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties. Sotalol is a nonselective beta-adrenergic receptor and potassium channel antagonist. In the heart, this agent inhibits chronotropic and inotropic effects thereby slowing the heart rate and decreasing myocardial contractility. This agent also reduces sinus rate, slows conduction in the atria and in the atrioventricular (AV) node and increases the functional refractory period of the AV node.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61949

CAS_Registry

3930-20-9

CHEBI_ID

CHEBI:63622

Chemical_Formula

C12H20N2O3S

code

C61949

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties. Sotalol is a nonselective beta-adrenergic receptor and potassium channel antagonist. In the heart, this agent inhibits chronotropic and inotropic effects thereby slowing the heart rate and decreasing myocardial contractility. This agent also reduces sinus rate, slows conduction in the atria and in the atrioventricular (AV) node and increases the functional refractory period of the AV node.

FDA_UNII_Code

A6D97U294I

FULL_SYN

SOTALOL

Sotalol

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29463

label

Sotalol

Legacy Concept Name

Sotalol

Preferred_Name

Sotalol

prefixIRI

Thesaurus:C61949

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0037707

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29576

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93038

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_63622 OBA LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148334 ODAE LOOM
http://purl.jp/bio/4/id/200906005348366490 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/9947 RXNORM LOOM
http://purl.obolibrary.org/obo/OMIT_0013902 OMIT LOOM
https://go.drugbank.com/drugs/DB00489 MDM LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClasse4826afc_5553_422c_8e97_28d6173cb5d3 WWECA LOOM
http://purl.bioontology.org/ontology/VANDF/4020814 VANDF LOOM
http://www.co-ode.org/ontologies/galen#Sotalol GALEN LOOM
http://stirdf.jst.go.jp/id/200907004781229232 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-804E0 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013015 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.100.291.805 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148334 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63622 ODNAE LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.063.291.805 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/C07AA07 ATC LOOM
http://purl.obolibrary.org/obo/MESH_D013015 BERO LOOM
http://www.drugbank.ca/drugs/DB00489 FTC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003385 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/D013015 MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP16279-9 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C61949 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0037707 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/004111 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/x01CG RCD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015652 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11535 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372911006 SNOMEDCT LOOM