National Cancer Institute Thesaurus

Last uploaded: May 28, 2019
Preferred Name

Miglitol

Synonyms

Glyset

Miglitol

MIGLITOL

Definitions

A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61847

CAS_Registry

72432-03-2

Chemical_Formula

C8H17NO5

code

C61847

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed.

FDA_UNII_Code

0V5436JAQW

FULL_SYN

Glyset

Miglitol

MIGLITOL

label

Miglitol

Legacy_Concept_Name

Miglitol

Preferred_Name

Miglitol

prefixIRI

ncit:C61847

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0066535

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2846

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http://mimi.case.edu/ontologies/2009/9/DrugOntology#miglitol SDO LOOM
http://purl.bioontology.org/ontology/MESH/C045621 MESH LOOM
http://www.drugbank.ca/drugs/DB00491 FTC LOOM
http://purl.jp/bio/4/id/200906081347613823 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/30009 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/109071007 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C045621 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_6935 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6935 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6935 CHEBI LOOM
http://purl.bioontology.org/ontology/UATC/A10BF02 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4021063 VANDF LOOM
http://purl.obolibrary.org/obo/dinto_DB00491 DINTO LOOM
https://bioportal.bioontology.org/ontologies/DMTO.owl#DMTO_0000922 DMTO LOOM
http://purl.obolibrary.org/obo/DRON_00011113 DRON LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#DMTO_0000922 FASTO LOOM
https://bioportal.bioontology.org/ontologies/DMTO.owl#DMTO_0001537 DMTO LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#DMTO_0001537 FASTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148526 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907037713722651 IOBC LOOM