National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Miglitol

Synonyms

Glyset

MIGLITOL

Miglitol

Definitions

A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61847

CAS_Registry

72432-03-2

Chemical_Formula

C8H17NO5

code

C61847

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed.

FDA_UNII_Code

0V5436JAQW

FULL_SYN

Glyset

MIGLITOL

Miglitol

label

Miglitol

Legacy Concept Name

Miglitol

NCI_Drug_Dictionary_ID

775336

PDQ_Closed_Trial_Search_ID

775336

PDQ_Open_Trial_Search_ID

775336

Preferred_Name

Miglitol

prefixIRI

Thesaurus:C61847

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0066535

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2846

Delete Subject Author Type Created
No notes to display