National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Mepivacaine

Synonyms

MEPIVACAINE

Mepivacaine

Definitions

An amide-type local anesthetic agent. At the injection site, mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61831

CAS_Registry

96-88-8

CHEBI_ID

CHEBI:6759

Chemical_Formula

C15H22N2O

code

C61831

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An amide-type local anesthetic agent. At the injection site, mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.

FDA_UNII_Code

B6E06QE59J

FULL_SYN

MEPIVACAINE

Mepivacaine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47602

label

Mepivacaine

Legacy Concept Name

Mepivacaine

Preferred_Name

Mepivacaine

prefixIRI

Thesaurus:C61831

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0025384

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C245

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/MESH_D008619 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.621.450 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001813 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C61831 BERO LOOM
http://purl.bioontology.org/ontology/LNC/LP14721-2 LOINC LOOM
http://purl.bioontology.org/ontology/NDDF/004567 NDDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018289 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/59560006 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008619 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00961 MDM LOOM
http://purl.jp/bio/4/id/200906097014176470 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0009683 OMIT LOOM
http://purl.bioontology.org/ontology/MESH/D008619 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/6759 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 DOID LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 HHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6759 NIFSTD LOOM
http://purl.bioontology.org/ontology/VANDF/4019815 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147904 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/N01BB03 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025384 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7971 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Mepivacaine GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-6B050 SNMI LOOM
http://www.drugbank.ca/drugs/DB00961 FTC LOOM
http://stirdf.jst.go.jp/id/200907000348691821 IOBC LOOM