National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Ketotifen

Synonyms

KETOTIFEN

Ketotifen

Alaway

Definitions

A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61799

CAS_Registry

34580-13-7

Chemical_Formula

C19H19NOS

code

C61799

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.

FDA_UNII_Code

X49220T18G

FULL_SYN

KETOTIFEN

Ketotifen

Alaway

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47579

label

Ketotifen

Legacy_Concept_Name

Ketotifen

Preferred_Name

Ketotifen

prefixIRI

ncit:C61799

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0022642

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29578

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http://purl.jp/bio/4/id/200906066742697174 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/6146 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D007665 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.621.370 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7083 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.778.370 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0022642 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4021170 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/003742 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372642003 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Ketotifen GALEN LOOM
http://childhealthservicemodels.eu/asthma#MOCHA-Asthma_000118 AO LOOM
http://purl.obolibrary.org/obo/dinto_DB00920 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.903.370 RH-MESH LOOM
http://d-nb.info/gnd/4163678-8 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RCD/x02LJ RCD LOOM
http://www.drugbank.ca/drugs/DB00920 FTC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148619 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907039373981714 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007665 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00017034 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00017034 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_92511 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_92511 CHEBI LOOM
http://purl.bioontology.org/ontology/UATC/S01GX08 ATC LOOM
http://purl.bioontology.org/ontology/UATC/R06AX17 ATC LOOM