loading...| Preferred Name |
Gentian Violet |
|
| Synonyms |
Crystal Violet Basic Violet 3 Hexamethyl-P-Rosaniline Chloride Gentian Violet GENTIAN VIOLET CI 42555 Genapax |
|
| Definitions |
A blue, aniline-derived dye with antifungal and antimitotic properties. Gentian violet (GV) dissociates into positive (GV+) and negative ions (Cl-) that penetrate both gram-positive and gram-negative bacterial cells. The GV+ ions interact with negatively charged components of the bacterial cell wall including lipopolysaccharide, peptidoglycan and DNA. This agent is also a mutagen and mitotic poison. GV elicits a photodynamic action mediated by a free-radical mechanism. Furthermore, this agent dissipates the action potential on prokaryotic or eukaryotic membranes by inducing permeability, thereby leading to respiratory inhibition and subsequent cell death. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61776 |
|
| CAS_Registry |
548-62-9 |
|
| Chemical_Formula |
C25H30N3.Cl |
|
| code |
C61776 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A blue, aniline-derived dye with antifungal and antimitotic properties. Gentian violet (GV) dissociates into positive (GV+) and negative ions (Cl-) that penetrate both gram-positive and gram-negative bacterial cells. The GV+ ions interact with negatively charged components of the bacterial cell wall including lipopolysaccharide, peptidoglycan and DNA. This agent is also a mutagen and mitotic poison. GV elicits a photodynamic action mediated by a free-radical mechanism. Furthermore, this agent dissipates the action potential on prokaryotic or eukaryotic membranes by inducing permeability, thereby leading to respiratory inhibition and subsequent cell death. |
|
| FDA_UNII_Code |
J4Z741D6O5 |
|
| FULL_SYN |
Crystal Violet Basic Violet 3 Hexamethyl-P-Rosaniline Chloride Gentian Violet GENTIAN VIOLET CI 42555 Genapax |
|
| label |
Gentian Violet |
|
| Legacy Concept Name |
Gentian_Violet |
|
| NSC Number |
3090 |
|
| Preferred_Name |
Gentian Violet |
|
| prefixIRI |
Thesaurus:C61776 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Indicator, Reagent, or Diagnostic Aid |
|
| UMLS_CUI |
C0017440 |
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| subClassOf |