National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dextrothyroxine

Synonyms

Dextrothyroxine

DEXTROTHYROXINE

Definitions

The dextrorotary isomer of thyroxine, a thyroid hormone with antihyperlipidemic activity. Dextrothyroxine stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. This results in a reduction in serum cholesterol and LDL.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61719

CAS_Registry

51-49-0

CHEBI_ID

CHEBI:30659

Chemical_Formula

C15H11I4NO4

code

C61719

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The dextrorotary isomer of thyroxine, a thyroid hormone with antihyperlipidemic activity. Dextrothyroxine stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. This results in a reduction in serum cholesterol and LDL.

FDA_UNII_Code

4W9K63FION

FULL_SYN

Dextrothyroxine

DEXTROTHYROXINE

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65373

label

Dextrothyroxine

Legacy Concept Name

Dextrothyroxine

Preferred_Name

Dextrothyroxine

prefixIRI

Thesaurus:C61719

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0011824

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1553

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