Preferred Name |
Dextrothyroxine |
|
Synonyms |
Dextrothyroxine DEXTROTHYROXINE |
|
Definitions |
The dextrorotary isomer of thyroxine, a thyroid hormone with antihyperlipidemic activity. Dextrothyroxine stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. This results in a reduction in serum cholesterol and LDL. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61719 |
|
CAS_Registry |
51-49-0 |
|
CHEBI_ID |
CHEBI:30659 |
|
Chemical_Formula |
C15H11I4NO4 |
|
code |
C61719 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
The dextrorotary isomer of thyroxine, a thyroid hormone with antihyperlipidemic activity. Dextrothyroxine stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. This results in a reduction in serum cholesterol and LDL. |
|
FDA_UNII_Code |
4W9K63FION |
|
FULL_SYN |
Dextrothyroxine DEXTROTHYROXINE |
|
Has_Salt_Form | ||
label |
Dextrothyroxine |
|
Legacy Concept Name |
Dextrothyroxine |
|
Preferred_Name |
Dextrothyroxine |
|
prefixIRI |
Thesaurus:C61719 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0011824 |
|
subClassOf |