loading...| Preferred Name |
Cromolyn |
|
| Synonyms |
4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo)- Cromoglycate 1,3-Bis(2-carboxychromon-5-yloxy)-2-hydroxypropane 1,3-Di(2-carboxy-4-oxochromen-5-yloxy)propan-2-ol CROMOLYN Cromolyn |
|
| Definitions |
A synthetic mast cell stabilizer with anti-inflammatory activity. Cromolyn probably interferes with the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in type I allergic reactions. Cromolyn also prevents inflammatory mediator release from eosinophils. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61691 |
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| CAS_Registry |
16110-51-3 |
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| CHEBI_ID |
CHEBI:59773 |
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| Chemical_Formula |
C23H16O11 |
|
| code |
C61691 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
A synthetic mast cell stabilizer with anti-inflammatory activity. Cromolyn probably interferes with the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in type I allergic reactions. Cromolyn also prevents inflammatory mediator release from eosinophils. |
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| FDA_UNII_Code |
Y0TK0FS77W |
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| FULL_SYN |
4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo)- Cromoglycate 1,3-Bis(2-carboxychromon-5-yloxy)-2-hydroxypropane 1,3-Di(2-carboxy-4-oxochromen-5-yloxy)propan-2-ol CROMOLYN Cromolyn |
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| Has_Salt_Form | ||
| label |
Cromolyn |
|
| Legacy Concept Name |
Cromolyn |
|
| Preferred_Name |
Cromolyn |
|
| prefixIRI |
Thesaurus:C61691 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0086073 |
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| subClassOf |