loading...| Preferred Name |
Citalopram |
|
| Synonyms |
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile CITALOPRAM Cipram Citalopram Lu 10-171 Nitalapram |
|
| Definitions |
A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61680 |
|
| CAS_Registry |
59729-33-8 |
|
| CHEBI_ID |
CHEBI:3723 |
|
| Chemical_Formula |
C20H21FN2O |
|
| code |
C61680 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects. |
|
| FDA_UNII_Code |
0DHU5B8D6V |
|
| FULL_SYN |
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile CITALOPRAM Cipram Citalopram Lu 10-171 Nitalapram |
|
| Has_Salt_Form | ||
| label |
Citalopram |
|
| Legacy Concept Name |
Citalopram |
|
| Preferred_Name |
Citalopram |
|
| prefixIRI |
Thesaurus:C61680 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0008845 |
|
| subClassOf |