Carboprost

Prostin 15M

Methyl-PGF2-alpha

(15S)-15-Methyl-PGF2alpha

CARBOPROST

Carboprost

U 32921

The (15S)-15 methyl analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha) with oxytocic activity. Mimicking endogenous PGF2 alpha, carboprost activates prostaglandin F receptor, a G-protein coupled receptor, on smooth muscle cells, thereby resulting in smooth muscle contractions. When administered intramuscularly on gravid subjects, this agent induces myometrium contractions, thereby initiating luteolysis and consequently parturition. Furthermore, carboprost's action on vascular smooth muscle and gastrointestinal tract sphincters leads to raised blood pressure and induces vomiting or diarrhea, respectively.

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61662

35700-23-3

CHEBI:3403

C21H36O5

C61662

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

FDA

The (15S)-15 methyl analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha) with oxytocic activity. Mimicking endogenous PGF2 alpha, carboprost activates prostaglandin F receptor, a G-protein coupled receptor, on smooth muscle cells, thereby resulting in smooth muscle contractions. When administered intramuscularly on gravid subjects, this agent induces myometrium contractions, thereby initiating luteolysis and consequently parturition. Furthermore, carboprost's action on vascular smooth muscle and gastrointestinal tract sphincters leads to raised blood pressure and induces vomiting or diarrhea, respectively.

7B5032XT6O

Prostin 15M

Methyl-PGF2-alpha

(15S)-15-Methyl-PGF2alpha

CARBOPROST

Carboprost

U 32921

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47433

Carboprost

Carboprost

Carboprost

Thesaurus:C61662

Pharmacologic Substance

C0007047

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78568