loading...| Preferred Name |
Bisoprolol |
|
| Synonyms |
BISOPROLOL Bisoprolol |
|
| Definitions |
A selective beta-1 adrenergic receptor antagonist with antihypertensive activity and devoid of intrinsic sympathomimetic activity. Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevent the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61653 |
|
| CAS_Registry |
66722-44-9 |
|
| CHEBI_ID |
CHEBI:3127 |
|
| Chemical_Formula |
C18H31NO4 |
|
| code |
C61653 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A selective beta-1 adrenergic receptor antagonist with antihypertensive activity and devoid of intrinsic sympathomimetic activity. Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevent the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
|
| FDA_UNII_Code |
Y41JS2NL6U |
|
| FULL_SYN |
BISOPROLOL Bisoprolol |
|
| Has_Salt_Form | ||
| label |
Bisoprolol |
|
| Legacy Concept Name |
Bisoprolol |
|
| Preferred_Name |
Bisoprolol |
|
| prefixIRI |
Thesaurus:C61653 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0053799 |
|
| subClassOf |