loading...| Preferred Name |
Antazoline |
|
| Synonyms |
4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine 2-Phenyl-benzyl-amino-methylimidazolin 2-(N-Phenyl-N-benzylaminomethyl)imidazoline 2-(N-Benzylanilinomethyl)-2-imidazoline 5512-M ANTAZOLINE Antazoline |
|
| Definitions |
An ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, and gastrointestinal and bronchial smooth muscles. These histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Antazoline is used to provide symptomatic relieve of allergic symptoms. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61638 |
|
| CAS_Registry |
91-75-8 |
|
| Chemical_Formula |
C17H19N3 |
|
| code |
C61638 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
An ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, and gastrointestinal and bronchial smooth muscles. These histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Antazoline is used to provide symptomatic relieve of allergic symptoms. |
|
| FDA_UNII_Code |
DHA8014SS1 |
|
| FULL_SYN |
4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine 2-Phenyl-benzyl-amino-methylimidazolin 2-(N-Phenyl-N-benzylaminomethyl)imidazoline 2-(N-Benzylanilinomethyl)-2-imidazoline 5512-M ANTAZOLINE Antazoline |
|
| Has_Salt_Form |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76668 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95310 |
|
| label |
Antazoline |
|
| Legacy Concept Name |
Antazoline |
|
| Preferred_Name |
Antazoline |
|
| prefixIRI |
Thesaurus:C61638 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0003143 |
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| subClassOf |