loading...| Preferred Name |
Metformin |
|
| Synonyms |
N,N-Dimethylimidodicarbonimidic Diamide 1,1-Dimethylbiguanide N,N-dimethylbiguanide METFORMIN Metformin metformin |
|
| Definitions |
An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61612 |
|
| ALT_DEFINITION |
A specific agent belonging to the biguanide class of antihyperglycemic agents The active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body's use of the glucose. Metformin is a type of antidiabetic agent. |
|
| CAS_Registry |
657-24-9 |
|
| CHEBI_ID |
CHEBI:6801 |
|
| Chemical_Formula |
C4H11N5 |
|
| code |
C61612 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191405 |
|
| Contributing_Source |
ACC/AHA CTRP FDA GDC |
|
| DEFINITION |
An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys. |
|
| Display_Name |
Metformin |
|
| FDA_UNII_Code |
9100L32L2N |
|
| FULL_SYN |
N,N-Dimethylimidodicarbonimidic Diamide 1,1-Dimethylbiguanide N,N-dimethylbiguanide METFORMIN Metformin metformin |
|
| Has_ACC-AHA_SARS2_Authorized_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 |
|
| Has_Salt_Form | ||
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Metformin |
|
| Legacy Concept Name |
Metformin |
|
| Maps_To |
Metformin |
|
| Preferred_Name |
Metformin |
|
| prefixIRI |
Thesaurus:C61612 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0025598 |
|
| subClassOf |