National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Meloxicam

Synonyms

4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

MELOXICAM

Meloxicam

Mobec

Mobic

Mobicox

Movalis

Movatec

Definitions

An oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of meloxicam.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61439

CAS_Registry

71125-38-7

Chemical_Formula

C14H13N3O4S2

code

C61439

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

An oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of meloxicam.

Display_Name

Meloxicam

FDA_UNII_Code

VG2QF83CGL

FULL_SYN

4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

MELOXICAM

Meloxicam

Mobec

Mobic

Mobicox

Movalis

Movatec

Has_Target

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17984

label

Meloxicam

Legacy Concept Name

Meloxicam

NCI_Drug_Dictionary_ID

472195

PDQ_Closed_Trial_Search_ID

472195

PDQ_Open_Trial_Search_ID

472195

Preferred_Name

Meloxicam

prefixIRI

Thesaurus:C61439

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0083381

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1323

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_6741 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_6741 CHEBI LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02648 MIO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148649 NDFRT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026398 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/galen#Meloxicam GALEN LOOM
http://purl.obolibrary.org/obo/CHEBI_6741 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6741 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_6741 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6741 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_6741 DRON LOOM
http://purl.jp/bio/4/id/200906074183368214 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387055000 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB00814 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0083381 OCHV LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000472195 PDQ LOOM
http://purl.obolibrary.org/obo/NCIT_C61439 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D000077239 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15390 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/41493 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/M01AC06 ATC LOOM
http://stirdf.jst.go.jp/id/200907020372388235 IOBC LOOM
http://purl.bioontology.org/ontology/RCD/j2n.. RCD LOOM
http://purl.bioontology.org/ontology/VANDF/4021203 VANDF LOOM
http://purl.obolibrary.org/obo/dinto_DB00814 DINTO LOOM
http://www.drugbank.ca/drugs/DB00814 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C065757 RH-MESH LOOM
http://scai.fraunhofer.de/AlzheimerOntology#meloxicam ADO LOOM
http://purl.bioontology.org/ontology/NDDF/006272 NDDF LOOM