National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Glycopeptide Antibiotic

Synonyms

Glycopeptide Antibiotic

Definitions

One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic nonribosomal peptide. These antibiotics inhibit the cell wall structure of susceptible organisms (principally Gram-positive cocci) by inhibiting peptidoglycan synthesis. First-generation glycopeptide antibiotics include vancomycin, teicoplanin, and ramoplanin; second-generation semi-synthetic glycopeptide antibiotics include oritavancin, dalbavancin, and telavancin.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61101

code

C61101

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

DEFINITION

One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic nonribosomal peptide. These antibiotics inhibit the cell wall structure of susceptible organisms (principally Gram-positive cocci) by inhibiting peptidoglycan synthesis. First-generation glycopeptide antibiotics include vancomycin, teicoplanin, and ramoplanin; second-generation semi-synthetic glycopeptide antibiotics include oritavancin, dalbavancin, and telavancin.

FULL_SYN

Glycopeptide Antibiotic

label

Glycopeptide Antibiotic

Legacy Concept Name

Glycopeptide_Antibiotic

NCI_Drug_Dictionary_ID

468927

PDQ_Closed_Trial_Search_ID

468927

PDQ_Open_Trial_Search_ID

468927

Preferred_Name

Glycopeptide Antibiotic

prefixIRI

Thesaurus:C61101

Semantic_Type

Organic Chemical

Chemical Viewed Functionally

UMLS_CUI

C0162724

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C258

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