National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Leukotriene

Synonyms

Leukotriene

Definitions

Any eicosanoid produced by the oxidation of either eicosapentaenoic acid (EPA) or arachidonic acid (AA) by arachidonate 5-lipoxygenase in leukocytes. Leukotrienes act locally as autocrine or paracrine hormones to modulate immune responses and inflammation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C608

CHEBI_ID

CHEBI:25029

code

C608

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Any eicosanoid produced by the oxidation of either eicosapentaenoic acid (EPA) or arachidonic acid (AA) by arachidonate 5-lipoxygenase in leukocytes. Leukotrienes act locally as autocrine or paracrine hormones to modulate immune responses and inflammation.

Display_Name

Leukotriene

FULL_SYN

Leukotriene

label

Leukotriene

Legacy Concept Name

Leukotriene

Preferred_Name

Leukotriene

prefixIRI

Thesaurus:C608

Semantic_Type

Organic Chemical

Biologically Active Substance

UMLS_CUI

C0023545

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C463

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