National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Therapeutic Hydrocortisone
Synonyms

(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione

Therapeutic Hydrocortisone

Hydrocortone

hydrocortisone

HYDROCORTISONE

Hydrocortisone

Aeroseb-HC

Barseb HC

Barseb-HC

Cetacort

Cort-Dome

Cortef

Cortenema

Cortifan

Cortisol

Cortispray

Cortril

Dermacort

Domolene

Eldecort

Hautosone

Heb-Cort

Hytone

Komed-HC

Nutracort

Proctocort

Rectoid
Definitions

A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04)
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C555
ALT_DEFINITION

A drug used to relieve the symptoms of certain hormone shortages and to suppress an immune response.
CAS_Registry

50-23-7
CHEBI_ID

CHEBI:17650
Chemical_Formula

C21H30O5
code

C555
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192234

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537
Contributing_Source

CTRP

FDA

GDC

HemOnc

OORO
DEFINITION

A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04)
Display_Name

Therapeutic Hydrocortisone
FDA_UNII_Code

WI4X0X7BPJ
FULL_SYN

(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione

Therapeutic Hydrocortisone

Hydrocortone

hydrocortisone

HYDROCORTISONE

Hydrocortisone

Aeroseb-HC

Barseb HC

Barseb-HC

Cetacort

Cort-Dome

Cortef

Cortenema

Cortifan

Cortisol

Cortispray

Cortril

Dermacort

Domolene

Eldecort

Hautosone

Heb-Cort

Hytone

Komed-HC

Nutracort

Proctocort

Rectoid
Has_Target

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17071
Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909
label

Therapeutic Hydrocortisone
Legacy Concept Name

Therapeutic_Hydrocortisone
Maps_To

Therapeutic Hydrocortisone
NCI_Drug_Dictionary_ID

39274
NSC Number

10482

10483
PDQ_Closed_Trial_Search_ID

39274
PDQ_Open_Trial_Search_ID

39274
Preferred_Name

Therapeutic Hydrocortisone
prefixIRI

Thesaurus:C555
Semantic_Type

Organic Chemical

Pharmacologic Substance
UMLS_CUI

C0020268
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521
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