National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Potassium-Sparing Diuretic

Synonyms

Potassium-Sparing Diuretic

Definitions

Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49186

code

C49186

DEFINITION

Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.

FULL_SYN

Potassium-Sparing Diuretic

label

Potassium-Sparing Diuretic

Legacy Concept Name

Potassium-Sparing_Diuretic

Preferred_Name

Potassium-Sparing Diuretic

prefixIRI

Thesaurus:C49186

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C3536751

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C448

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