loading...| Preferred Name |
Vecuronium Bromide |
|
| Synonyms |
Vercuronium Piperidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-, Bromide VECURONIUM BROMIDE Vecuronium Bromide NC-45 Norcuron |
|
| Definitions |
The bromide salt form of vecuronium, a synthetic steroid derivative of the naturally occurring alkaloids of curare with a muscle relaxant property. Vecuronium bromide competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This leads to skeletal muscle relaxation and paralysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47782 |
|
| CAS_Registry |
50700-72-6 |
|
| CHEBI_ID |
CHEBI:9940 |
|
| Chemical_Formula |
C34H57N2O4.Br |
|
| code |
C47782 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 |
|
| Contributing_Source |
CPTAC FDA |
|
| DEFINITION |
The bromide salt form of vecuronium, a synthetic steroid derivative of the naturally occurring alkaloids of curare with a muscle relaxant property. Vecuronium bromide competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This leads to skeletal muscle relaxation and paralysis. |
|
| FDA_UNII_Code |
7E4PHP5N1D |
|
| FULL_SYN |
Vercuronium Piperidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-, Bromide VECURONIUM BROMIDE Vecuronium Bromide NC-45 Norcuron |
|
| label |
Vecuronium Bromide |
|
| Legacy Concept Name |
Vecuronium_Bromide |
|
| NCI_Drug_Dictionary_ID |
740778 |
|
| PDQ_Closed_Trial_Search_ID |
740778 |
|
| PDQ_Open_Trial_Search_ID |
740778 |
|
| Preferred_Name |
Vecuronium Bromide |
|
| prefixIRI |
Thesaurus:C47782 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0042435 |
|
| subClassOf |