National Cancer Institute Thesaurus

Last uploaded: February 4, 2019
Preferred Name

Sulfamethoxazole

Synonyms

Radonil

SULFAMETHOXAZOLE

Gamazole

Metoxal

Sulfisomezole

Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-

Sulfanilamide, N'-(5-methyl-3-isoxazolyl)-

Sulfamethoxazole

Definitions

A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47737

CAS_Registry

723-46-6

CHEBI_ID

CHEBI:9332

Chemical_Formula

C10H11N3O3S

code

C47737

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.

FDA_UNII_Code

JE42381TNV

FULL_SYN

Radonil

SULFAMETHOXAZOLE

Gamazole

Metoxal

Sulfisomezole

Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-

Sulfanilamide, N'-(5-methyl-3-isoxazolyl)-

Sulfamethoxazole

label

Sulfamethoxazole

Legacy_Concept_Name

Sulfamethoxazole

NSC_Code

147832

Preferred_Name

Sulfamethoxazole

prefixIRI

ncit:C47737

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0038689

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29739

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http://purl.bioontology.org/ontology/RXNORM/10180 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/2832-6127 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013420 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.146.807.867 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/002827 NDDF LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9332 NIFSTD LOOM
http://purl.bioontology.org/ontology/LNC/LP14550-5 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146102 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.700.725.867 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4017734 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/70047000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55940 SNMI LOOM
http://purl.bioontology.org/ontology/UATC/J01EC01 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D013420 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.884.725.867 RH-MESH LOOM
http://purl.jp/bio/4/id/200906081612233728 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001572 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/363528007 SNOMEDCT LOOM