loading...| Preferred Name |
Prilocaine |
|
| Synonyms |
o-Propionotoluidide, 2-(propylamino)- Propitocaine 6,7-Epoxytropine Tropate o-Methyl-alpha-propylaminopropionanilide Propanamide, N-(2-methylphenyl)-2-(propylamino)-(9CI) PRILOCAINE Prilocaine |
|
| Definitions |
A toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated sodium channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47685 |
|
| CAS_Registry |
721-50-6 |
|
| CHEBI_ID |
CHEBI:8404 |
|
| Chemical_Formula |
C13H20N2O |
|
| code |
C47685 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated sodium channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses. |
|
| FDA_UNII_Code |
046O35D44R |
|
| FULL_SYN |
o-Propionotoluidide, 2-(propylamino)- Propitocaine 6,7-Epoxytropine Tropate o-Methyl-alpha-propylaminopropionanilide Propanamide, N-(2-methylphenyl)-2-(propylamino)-(9CI) PRILOCAINE Prilocaine |
|
| Has_Salt_Form | ||
| label |
Prilocaine |
|
| Legacy Concept Name |
Prilocaine |
|
| NSC Number |
40027 |
|
| Preferred_Name |
Prilocaine |
|
| prefixIRI |
Thesaurus:C47685 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0033124 |
|
| subClassOf |