National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pindolol

Synonyms

1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol

Carvisken

PINDOLOL

Pindolol

Visken

Definitions

An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47673

CAS_Registry

13523-86-9

CHEBI_ID

CHEBI:8214

Chemical_Formula

C14H20N2O2

code

C47673

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors.

FDA_UNII_Code

BJ4HF6IU1D

FULL_SYN

1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol

Carvisken

PINDOLOL

Pindolol

Visken

label

Pindolol

Legacy Concept Name

Pindolol

Preferred_Name

Pindolol

prefixIRI

Thesaurus:C47673

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0031937

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29576

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http://purl.obolibrary.org/obo/CHEBI_8214 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8214 NIFSTD LOOM
http://purl.bioontology.org/ontology/LNC/LP16255-9 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C47673 BERO LOOM
http://purl.bioontology.org/ontology/ATC/C07AA03 ATC LOOM
http://stirdf.jst.go.jp/id/200907099690715640 IOBC LOOM
http://www.drugbank.ca/drugs/DB00960 FTC LOOM
http://purl.jp/bio/4/id/200906073760449885 IOBC LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#pindolol SDO LOOM
http://www.co-ode.org/ontologies/galen#Pindolol GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-811D0 SNMI LOOM
http://purl.obolibrary.org/obo/OMIT_0011847 OMIT LOOM
http://purl.bioontology.org/ontology/RXNORM/8332 NLMVS LOOM
http://purl.bioontology.org/ontology/RXNORM/8332 RXNORM LOOM
https://go.drugbank.com/drugs/DB00960 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387102009 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9740 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.755.624.698.699 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.100.624.698.699 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147063 NDFRT LOOM
http://purl.obolibrary.org/obo/MESH_D010869 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0031937 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4018760 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/001857 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/bda.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010869 RH-MESH LOOM
http://purl.jp/bio/4/id/200906093628681036 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D010869 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015685 PMAPP-PMO LOOM
http://purl.jp/bio/4/id/200906075947024813 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.063.624.698.699 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907060127613462 IOBC LOOM
http://stirdf.jst.go.jp/id/200907045196615958 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU018207 LOINC LOOM