Preferred Name |
Pindolol |
|
Synonyms |
1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol Carvisken PINDOLOL Pindolol Visken |
|
Definitions |
An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47673 |
|
CAS_Registry |
13523-86-9 |
|
CHEBI_ID |
CHEBI:8214 |
|
Chemical_Formula |
C14H20N2O2 |
|
code |
C47673 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. |
|
FDA_UNII_Code |
BJ4HF6IU1D |
|
FULL_SYN |
1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol Carvisken PINDOLOL Pindolol Visken |
|
label |
Pindolol |
|
Legacy Concept Name |
Pindolol |
|
Preferred_Name |
Pindolol |
|
prefixIRI |
Thesaurus:C47673 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0031937 |
|
subClassOf |