National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Natamycin

Synonyms

Natamycin

Natacyn

Pimaricin

Myprozine

NATAMYCIN

Synogil

16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure

Delvolan

Definitions

A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47634

CAS_Registry

7681-93-8

Chemical_Formula

C33H47NO13

code

C47634

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect.

FDA_UNII_Code

8O0C852CPO

FULL_SYN

Natamycin

Natacyn

Pimaricin

Myprozine

NATAMYCIN

Synogil

16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure

Delvolan

label

Natamycin

Legacy_Concept_Name

Natamycin

Preferred_Name

Natamycin

prefixIRI

ncit:C47634

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0027444

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C514

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http://purl.bioontology.org/ontology/NDDF/002891 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372712006 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015102 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4018597 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_7488 CHEBI LOOM
http://purl.obolibrary.org/obo/dinto_DB00826 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.540.505.550 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP30647-9 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/G01AA02 ATC LOOM
http://purl.bioontology.org/ontology/UATC/S01AA10 ATC LOOM
http://purl.bioontology.org/ontology/UATC/A07AA03 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D010866 MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-96550 SNMI LOOM
http://www.co-ode.org/ontologies/galen#Natamycin GALEN LOOM
http://purl.bioontology.org/ontology/UATC/D01AA02 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146913 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/7268 RXNORM LOOM
http://purl.bioontology.org/ontology/RCD/x02Lz RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010866 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/A01AB10 ATC LOOM