loading...| Preferred Name |
Natamycin |
|
| Synonyms |
16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure Delvolan Myprozine NATAMYCIN Natacyn Natamycin Pimaricin Synogil |
|
| Definitions |
A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47634 |
|
| CAS_Registry |
7681-93-8 |
|
| Chemical_Formula |
C33H47NO13 |
|
| code |
C47634 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect. |
|
| FDA_UNII_Code |
8O0C852CPO |
|
| FULL_SYN |
16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure Delvolan Myprozine NATAMYCIN Natacyn Natamycin Pimaricin Synogil |
|
| label |
Natamycin |
|
| Legacy Concept Name |
Natamycin |
|
| Preferred_Name |
Natamycin |
|
| prefixIRI |
Thesaurus:C47634 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0027444 |
|
| subClassOf |